孙英健:
1970年1月出生,女,副教授,博士,北京农学院硕士生导师。中国畜牧兽医学会兽医药理与毒理学专业委员会理事。研究方向为兽医药理与毒理学。重点研究中药有效成分及作用机制。
主持课题
1、2011/01-2013/12,北京市人才强教深化项目—骨干教师子项目,阿维菌素对动物肠道屏障的功能影响,12万元。
2、2008/01-2010/12,北京市教委面上项目,P-糖蛋白在阿维菌素类药物的神经毒性中作用机制的研究,KM200810020005,13万元。
3、201501-201512,其他
发表文章和专利:
1. Yingjian Sun, Xiaoping Diao, Qidi Zhang, Jianzhong Shen. Bioaccumulation and elimination of Avermectin B1a in the earthworms (Eisenia fetida). Chemosphere, 60, (2005), 699-704(影响因子1.936、2.297)
2. 孙英健,沈建忠,张启迪,阿维菌素在蚯蚓体内的残留检测研究,中国农业科学(Scientia Agricultura Sinica)2004,37(10):1571-1574
3. 孙英健,刁小平,沈建忠,阿维菌素B1a对土壤微生物和蚯蚓的影响, 应用生态学报,2005,16(11):2140~2143
4. Ying-Jian Sun, Ding-Xin Long, Wei Li , Wei-Yuan Hou, Yi-Jun Wu, Jian-Zhong Shen,Effects of avermectins on neurite outgrowth in differentiating mouse neuroblastoma N2a cells,Toxicology Letters 192 (2010) 206–211 (IF:3.2)
5. 张银花,李秋明,孙英健*,埃普里诺霉素对N2a细胞增殖的影响,动物医学进展 2010,31(S):121-123
6. 孙英健, 张银花,动物福利与肉品卫生,扬州大学学报, 2008(29):14-17
7. 孙英健,李焕荣,学分制下的实验教学内容改革与实验教学管理的探讨,都市型农业中畜牧兽医本科专业教学改革探讨,中国农业出版社,2010,99-103
8. W Li, YJ Wu, DM Qin, Y Ma, YJ Sun, SP Qiu . A Method for Quantifying Azoxystrobin Residues in Grapes and Soil Using GC with Electron Capture Detection, Chromatographia, 2008,761-766 (IF:2.1)
9. Ying-Jian Sun, Hui-Ping Wang, Yu-Jie Liang, Lin Yang, Wei Li, Yi-Jun Wu. An NMR-based metabonomic investigation of the subacute effects of melamine in rats. J. Proteome Res. 2012, 11, 2544?2550 (IF5.4)
10.李焕荣,孙英健*. 都市农业环境下动物医学(兽医)专业人才培养的思考—以北京为例, 教育教学论坛,2012,10
11.Chen JX, Sun YJ, Wang P, Long DX, Li W, Li L, Wu YJ. Induction of autophagy by TOCP in differentiated human neuroblastoma cells lead to degradation of cytoskeletal components and inhibition of neurite outgrowth. Toxicology. 2013, 310:92-97. (IF:4.017)共同第一作者
12. 李增顺,宋繁,张银花,孙英健*,牛角地黄汤对α-溶血素诱导的红细胞溶血抑制作用研究,北京农学院学报,2015,30(1)
13. Wang HP, Liang YJ, Sun YJ, Hou WY, Chen JX, Long DX, Xu MY, Wu YJ. Subchronic neurotoxicity of chlorpyrifos, carbaryl and their combination in rats. Environmental Toxicology. 2013, 29(10):1193–1200
14.Luo L, Sun YJ, Yang L, Huang S, Wu YJ. Abamectin induces P-glycoprotein expression in S2 cells via calcium/calmodulin/NF-κB pathway. Chemico-Biological Interactions 2013, 203:430-439.
15.Wang HP, Liang YJ, Sun YJ, Chen JX, Hou WY, Long DX, Wu YJ. NMR-based metabonomic analysis of serum and and urine of rats following subchronic exposure to dichlorvos, deltamethrin, or a combination of these two pesticides. Chem-Biol Interact. 2013, 203:588-596.
16.Luo L, Sun YJ, Wu YJ. Abamectin resistance in Drosophila is related to increased expression of P-glycoprotein via the dEGFR and dAkt pathways. Insect Biochem Mol Biol. 2013, 43(8):627-634.
17.Chang PA, Sun YJ, Huang FF, Qin WZ, Chen YY, Zeng X, Wu YJ. Identification of human patatin-like phospholipase domaincontaining protein 1 and a mutant in human cervical cancer HeLa cells. Mol Biol Rep. 2013, 40:5597-5605.
18. Wang HP, Liang YJ, Sun YJ, Hou WY, Chen JX, Long DX, Xu MY, Wu YJ. Subchronic neurotoxicity of chlorpyrifos, carbaryl and their combination in rats. Environ Toxicol. 2014, 29(10): 1193-1200.
19. Wang P, Wang HP, Xu MY, Liang YJ, Sun YJ, Yang L, Li L, Li W, Wu YJ. Combined subchronic toxicity of dichlorvos with malathion or pirimicarb in mice liver and serum: a metabonomic study. Food Chem Toxicol 2014, 70:222-230.
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