安健,教授,博士,学科研究方向为预防兽医学,主攻兽医重要疾病免疫学、病原分子生物学、病原抗药性。入选北京市科技新星、北京市优秀人才和北京市优秀青年骨干教师,兼任中国畜牧兽医学会兽医病理学会常务理事、中国畜牧兽医学会家畜寄生虫学会理事,北京农学院教务处副处长。
主持的在研科研项目:国家自然科学基金项目“堆型艾美耳球虫外毒素ISCOMATRIX疫苗细胞免疫研究”,北京绿康牧生物科技有限公司项目“鸡、猪球虫病综合防治技术的建立”。
主持完成的科研项目:北京市自然基金项目、北京市教委项目、北京市青年骨干教师项目、北京市科干局项目、北京市科技新星项目、北京市委组织部项目、北京市动植物检验检疫局项目、国家质量监督检验检疫总局科技计划项目各一项。
参加完成的科研项目:国家科技“八五攻关”项目、国家科技“十五攻关”项目、国家“十一五”科技支撑重大项目各一项。
发表科技论文60多篇,主要论文如下:
1. Investigation on the prevalence of coccidiosis and maduramycin drug resistancein chickens in China, Veterinary parasitology, 2013.3
2. Heterologous expression of biologically active chicken granulocyte-macrophage colony stimulating factor in Pichia pastoris, African Journal of Biotechnology 2012.11
3. Toll-like receptor 2 type 1 and type 2 polymorphismsin different chicken breeds, Poultry Science 2012.91
4. Polymorphisms of chicken Toll-like receptors 4, 15, and 21 in different breeds, Poultry Science, 2012.91
5. Iscomatrix Application of Nanotechnology, Icbeb 2012
6. Expession of microneme protein 4 from Eimeria tenella in the methylotrophic yeast Pichia pastoris, Icbeb 2012
7. Ultrastructure of the gametogenesis of coccdiae Eimeria tenella, 12th Internationnal congress of protozoology, 2005.7
8. Studies on drug resistance of Eimeria tenella in china,12th Internationnal congress of protozoology, 2005.7
9. Studues on the purification and mRNA differential display of drug resistance of Eimeria tenella,112th Internationnal congress of protozoology, 2005.7
10. Study on the extraction of extractor–secretory antigen of Eimeria acervulina, Proceeding of the 10th International Coccidiosis Conference, 2010.10
11. Study on the relationship between the invasion of Eimeria tenella and the cell Aptosis, Proceeding of the 10th International Coccidiosis Conference, 2010.10
12. Expression and characterization of chicken cytokines in Pichia pastori, Proceeding of the 10th International Coccidiosis Conference, 2010.10
13.柔嫩艾美尔球虫配子发生的超微结构,动物学报,2001.4
14.柔嫩艾美尔球虫裂殖生殖阶段超微结构,畜牧兽医学报,2001.5
15.马杜霉素对不同虫株柔嫩艾美尔球虫的超微结构影响,畜牧兽医学报,2002.1
16.马杜霉素抗药性诱导的实验研究, 畜牧兽医学报,1997.4
17.柔嫩艾美耳球虫马杜拉霉素抗药株与敏感株的mRNA差异显示,畜牧兽医学报,2006.5
18.柔嫩艾美尔球虫免疫与鸡盲肠扁桃体GM-CSF的表达动态关系,畜牧兽医学报,2008.7
19.鸡IL_2的毕赤酵母表达和生物活性鉴定, 中国农学通报, 2010.26
20.马杜霉素对柔嫩艾美尔球虫的超微结构影响,中国兽医学报,2002.1
21.柔嫩艾美尔球虫大配子发育和卵囊的超微结构, 中国兽医学报, 2001.6
22.鸡IBV分子生物学研究进展, 中国兽医杂志, 2001.9
23.阿维菌素驱杀牛内寄生虫实验, 中国兽医杂志, 2002.1,
24.柔嫩艾美耳球虫的抗药性调查, 中国兽医杂志, 2004.6
25.犬肉旋毛虫的检验, 中国兽医杂志, 2004.10
26.球虫单孢子囊克隆技术的建立, 中国兽医杂志, 2006.2
27.球虫抗药性分子生物学检测技术的建立, 中国兽医学报, 2007.3
28.柔嫩艾美尔球虫免疫与鸡盲肠扁桃体IL-2的表达动态关系,中国兽医杂志,2008.7
29.鸡肿瘤坏死因子-α的原核表达及活性鉴定, 中国兽医杂志, 2011.9
30.鸡γ干扰素的原核表达与生物活性研究, 中国兽医杂志, 2010.3
31.粒细胞-巨噬细胞集落刺激因子与柔嫩艾美耳球虫免疫, 中国兽医学报, 2010.4
出版著作12部,主编4部,副主编7部,参编3部:
1. 主编《柔嫩艾美耳球虫与球虫病》中国农业出版社, 2008.5
2. 主编《鸡球虫病与球虫抗药性》中国农业出版社, 2011.4
3. 主编《怎样养鹦鹉》中华工商联合出版社, 2007.10
4. 主编《怎样养画眉》中华工商联合出版社, 2007.10
出版教材5部,副主编3部,参编3部:
1. 副主编《高级寄生虫学实验技术》中国科学技术出版社,2005.10
2. 副主编《兽医寄生虫病学》科学出版社,2009.6
3. 副主编《动物疾病病理诊断》中国科学技术出版社, 2001.7
获得国际发明专利2个:
1. 一种检测猪痢疾的实时荧光PCR试剂盒和寡核苷酸序列,2013.2
2. 一种检测猪痢疾的PCR试剂盒及引物, 2013.2
获得北京市教学成果二等奖,地方在京农林院校与央属农林院校人才培养共享机制创新与实践,2013获得北京农学院教学成果一等奖1项,地方在京农林院校与央属农林院校人才培养共享机制创新与实践,2012,二等奖1项,立体化网络课程建设管理体系构建与实施效果,2012
通讯地址:北京市昌平区回龙观北农路7号,北京农学院教务处,邮编:102206
办公(传真)电话:86-10-80795193,E-mail: anyh001@bac.edu.cn; anjian68@sina.com
CURRICULUM VITAE
Professor, Faculty Member, College of animal science and Veterinary Medicine, Beijing Uniersity of Agriculture, China.
RESEARCH EXPERIENCE:
1992-2003: Drug resistance of Eimeira tenella
1996-1997: The S and N protein of infectious bronchitis virus
2004-now: Control of Coccidiosis by recombination protein vaccine
2012-now: Control of Coccidiosis by Traditional Chinese Medicine
COMPETITIVE RESEARCH GRANTS
Co-investigator: Eighth-five-year foundation to tackle key problems in science and technology. (1992-1995). Drug resistance of Eimeira tenella. (Kong Fanyao as PI).
Principal Investigator: Bureau of science and cadre foundation of Beijing(1996-1997) The recombination protein expression of the S and N protein of infectious bronchitis virus
Co-investigator: Tenth-five-year foundation to tackle key problems in science and technology. (2001-2004). Research on drug resistance of Coccidia. (Wang Ming as PI).
Principal Investigator: Beijing Science novel star fund (2004-2006)
Principal Investigator: Beijing natural Science fund (2003-2007) Rapid test drug resistance of chick Coccidia
Principal Investigator: Beijing education committee Science fund (2007-2009)Research on cytokine immunity adjuvant on Eimeira tenella
Principal Investigator: National Science Foundation of China (2011-2013) Immunity research on the Exotoxin Iscomatrix vaccination of Eimeria aceverlina
HONORS, MEMBERSHIP IN PROFESSIONAL ORGANIZATIONS
2002-present: Scientific advisor for protect and control wild animal disease, Bureau of park and garden, beijing, China
2007-present: Scientific advisor for protect and control chicken disease, Beijing Huadu Broiler Lt. D, China
ORIGINAL PUBLICATIONS IN JOURNALS
1. Investigation on the prevalence of coccidiosis and maduramycin drug resistancein chickens in China, Veterinary parasitology, 2013.3
2. Heterologous expression of biologically active chicken granulocyte-macrophage colony stimulating factor in Pichia pastoris, African Journal of Biotechnology 2012.11
3. Toll-like receptor 2 type 1 and type 2 polymorphismsin different chicken breeds, Poultry Science 2012.91
4. Polymorphisms of chicken Toll-like receptors 4, 15, and 21 in different breeds, Poultry Science, 2012.91
5. Iscomatrix Application of Nanotechnology, Icbeb 2012
6. Expession of microneme protein 4 from Eimeria tenella in the methylotrophic yeast Pichia pastoris, Icbeb 2012
7. Ultrastructure of the gametogenesis of coccdiae Eimeria tenella, 12th Internationnal congress of protozoology, 2005.7
8. Studies on drug resistance of Eimeria tenella in china,12th Internationnal congress of protozoology, 2005.7
9. Studues on the purification and mRNA differential display of drug resistance of Eimeria tenella,112th Internationnal congress of protozoology, 2005.7
10. Study on the extraction of extractor–secretory antigen of Eimeria acervulina, Proceeding of the 10th International Coccidiosis Conference, 2010.10
11. Study on the relationship between the invasion of Eimeria tenella and the cell Aptosis, Proceeding of the 10th International Coccidiosis Conference, 2010.10
12. Expression and characterization of chicken cytokines in Pichia pastori, Proceeding of the 10th International Coccidiosis Conference, 2010.10
13. The ultrastructural effect of maduramasin to dufferent strains of Eimeria tenella. Chinese Journal of Animal and Veterinary Science, 2002
14. The ultrastructural effect of maduramasin to Eimeria tenella. Chinese Journal of Veterinary science, 2002
15. Experimental study on the development of resistance to maduramisin in Eimeria tenella. Chinese Journal of Animal and Veterinary Science, 1997
16. The ultrastructural studies on the merogony development of Eimeria tenella. Chinese Journal of Animal and Veterinary Science,2001
17. Ultra-structure of the gametogenesis of Coccidiae Eimeria tenella. Acta Zoologica Sinica, 2001
18. The ultrastructural studies on the macrogametogenesis and oocyst forming of Eimeria tenella Chinese Journal of Veterinary science 2001
BOOKS and MONOGRAPHS:
1. 1. Chicken Coccidiosis and drug resistance of chicken Coccidia. Chinese agricultural press,2011, ISBN 978-7-709-15584-8
2. 2. Eimeria tenella of chicken and Coccidiosis. Chinese agricultural press, 2008,ISBN 978-7-709-13176-7
Address:No.7, Beinong Road, Huilongguan, Changping, Beijing, 102206,P.R.C.
Phone:86-10-80795193;Fax:86-10-80795193;E-mail:anyh001@bac.edu.cn;
anjian68@sina.com.